Improving animal and human health and wellbeing across the lifecourse.
*CASE: These are CASE DTP studentships. As part of the programme, you will be required to undertake a placement with the CASE partner for a minimum of 3 months.
*AP: These are Standard DTP studentships with an associate partner where you will be required to spend time with each of the partners. You will be asked to apply to one of the partners (as listed in the ‘Host Institution’ column), but this is just for administration purposes. You will then be registered for your postgraduate studies at one of the partner universities of the lead supervisors. Your registered university will be confirmed by the DTP following the interview stage of the selection process.
*JD: This project in collaboration with the University of Bristol and the University of the West of England (UWE) is subject to a joint degree award. Successful applicants will be registered at both these institutions, and graduates will be awarded a joint degree from these two institutions upon successful completion of the PhD programme.
|PROJECT TITLE||MAIN / ROTHAMSTED / LEAD SUPERVISOR||HOST INSTITUTION||KEYWORDS|
|Aging before birth: identifying prenatal influences of lifestyle on telomeres and the epigenetic clock||Prof Rosalind John||Cardiff University||Fetal programming, Telomeres, Epigenetic clock, Maternal diet and nutrition, Healthy aging|
|Attributing the source of antimicrobial resistant diarrheal pathogens in African children||Prof Samuel Sheppard||University of Bath||Enteric bacteria, One Health, Host adaptation, Source attribution, Antimicrobial resistance|
|Autophagy control of human neuroinflammatory signalling pathways *AP *JD||Prof Jon Lane / Dr Lucy Crompton||University of Bristol (apply through here) / University of the West of England||Neuroinflammation, autophagy, glia, astrocytes, microglia|
|Building molecular transport machines regulated by autoinhibition and ligand-induced activation||Dr Mark P Dodding||University of Bristol||Biodesign, Microtubule Motor, Kinesin, Cell Biology, Synthetic Biology|
|Developing microbiological ammunition for robust decolonization of antibiotic resistant bacteria||Dr Ben Raymond||University of Exeter (Penryn)||Bacteriophage, antimicrobial resistance, AMR, antiobiotic resistance, evolution|
|HNRNPD: a master regulator of microRNAs in response to ischemic stress?||Prof Lorna Harries||University of Exeter (Streatham/St Luke’s)||MicroRNA, HNRNPD, genomics, cell biology, cell identity|
|How do untranslated regions of cannabinoid receptor type 1 mRNA determine receptor subcellular localisation and function||Prof Jeremy Henley||University of Bristol||mRNA trafficking and local translation, mRNA untranslated region (UTR), endocannabinoid system (ECS), Type 1 Cannabinoid receptor, Neuroscience|
|Investigating the molecular and synaptic mechanisms which underlie the sustained antidepressant effects of NMDA receptor antagonists *CASE||Prof Emma Robinson||University of Bristol||Rapid-acting antidepressants, animal behaviour, electrophysiology, molecular biology, affective neuroscience|
|Mechanism of Linoleic Acid protection against SARS-CoV-2 viral replication in human cells||Prof Paul Verkade||University of Bristol||Coronavirus, ultrastructural studies, correlative light and electron microscopy, cryo electron tomography, membrane remodelling|
|Non-genetic paternal effects on offspring reproduction and health: mechanisms and evolutionary consequences in a bird model system||Dr Barbara Tschirren||University of Exeter (Penryn)||Developmental Origins of Health, Epigenetics, Reproductive Health and Bird Behaviour, Fertility and Sustainable Animal Breeding, Mechanisms of Evolutionary Change|
|Pharmacophylogenomics: Developing phylogenies as predictive tools in drug discovery||Prof Davide Pisani||University of Bristol||Drug discovery, Phylogenetics, Bayesian statistics, Genomics, molecular evolution|
|Probing the molecular activation of complement component C5 using a novel antibody toolbox||Prof Jean van den Elsen||University of Bath||Innate immunity, Complement, Inflammation, Protein structure|
|Run, eat, sleep, repeat: Hypothalamic integration of homeostatic and circadian signals||Prof Hugh Piggins||University of Bristol||Exercise, feeding, melanocortins, circadian, sleep|
|Tackling antibiotic resistance through blocking of signalling pathways||Dr Susanne Gebhard||University of Bath||Microbiology, antibiotic resistance, signal transduction, drug development, molecular biology|
|Understanding GPCR signalling in mechanosensing and intestinal barrier function *AP *JD||Prof Anne Ridley / Dr Alexander Greenhough||University of Bristol (apply through here) / University of the West of England||Cell biology, Mechanosensing, Signalling, Omics, Bioinformatics|