Molecular Mechanisms & Pathways: Student cohort

 

Current Final Years

Meg Warden Ancestral functions of genes regulated by imprinting in mammals Akshita Jindal NetClamp: a new experimental tool to manipulate neural networks
Amy Amin Probing the function of dopaminergic inputs to the cerebellum Carolina Gaudenzi Interaction of Regulatory Factor X (RFX) factors and the mineralocorticoid receptor
David Alliband Autophagy control of human neuroinflammatory signalling pathways Niharika Singh How are astrocytes made? Transcriptional regulation of astrocyte specification across development and adulthood
Alexandre Pinto How do untranslated regions of cannabinoid receptor type 1 mRNA determinereceptor subcellular localisation and function Lucie Tkacova Investigating the Mitochondrial Basis of Neuronal ageing
Tanya Kaur Run, eat, sleep, repeat: Hypothalamic integration of homeostatic and circadian Salma Haniffa Visual-spatial processing within the retrosplenial cortex
Tom Gerrard Phenotypic and Genotypic diversity in Moraxella catarrhalis: Using Population Biology to Understand Antimicrobial Resistance and Pathogenesis Meg Sambrook Functional roles of presynaptic opioid receptors
Joe Flanagan Investigating the molecular and synaptic mechanisms which underlie the sustained antidepressant effects of NMDA receptor antagonists Iwan Williams Cutting edge novel technologies to investigate lysosomal channels and transporters important in recovery post-autophagy

Current Third Years

Chenxing Jiang Unravelling the molecular mechanisms of organelle communication in the regulation of cellular lipid metabolism and developmental processes Elsa Oakes The cellular and synaptic mechanisms for the effects of psychedelics on flexible memory representations in the hippocampus
James Boyd Genetic Engineering Tumour Infiltrating Lymphocytes (TILs) to achieve enhanced tumour killing Rabia Sevil Investigating the role of senescence in musculoskeletal ageing
Ben Murcott Understanding the genetic basis of reproductive strategy in a parasitic nematode system Ríona Burke Non-genetic paternal effects on offspring reproduction and health: mechanisms and evolutionary consequences in a bird model system
Cameron Haddow Molecular mechanisms of the ubiquitin system Selina Diether Understanding receptor-mediated mechanosensing and signalling in cell barrier function during tissue homeostasis and stress responses
Hanady Nehme Understanding the Role of Extracellular Vesicle/Exosome Transport in the Visual System Jennika Bates Exploring genotype-phenotype correlations in Sox10 mutations

Current Second Years

Emily Davis Studying early human embryo development using stem cell models Fotis Gkoutzourelas Decoding secret conversations inside cells: Understanding how organelle interactions in human cells are regulated during the cell cycle
Chelsea Stevens Imaging analysis of muscle progenitor and stem cell activation in differentiation and repair Jonathan Odira Osano Sub-cellular localisation and functional effects of micro/nanoplastics on aquaculture fish with coherent Raman microscopy
Ajay Elamaran The molecular basis of host manipulation by a parasitic worm Kelli Gallacher Enhancing MITF transcription factor activity using protein engineering to investigate melanocyte development and improve melanoma treatment
Andrew Cadzow Time-resolved kinetic and structural understanding of essential enzymes to develop novel herbicides Tom Jenniches Perez Mass Spectrometry Imaging of Enzyme Activity in Brain and Beyond
Foteini Xeni Ageing and body clock rhythms: The importance of a social network Morgan Jones The arthropod megaphylogeny and the origin of Earth’s biodiversity
Emilee Sinkala Divergent sleep behaviour – An evolutionary approach to understand why we sleep George Mather Characterising the role of in vivo cell-to-cell communication in the stress system
Florrie Newman Investigating the role of neuronal metabolism in excitation/inhibition balance Tom Duffy Combining artificial intelligence based drug discovery and automated patch clamping to revolutionise our understanding of lysosomal ion channels
Gabi Bergmane How do GluD1 glutamate receptors in the hippocampal CA2 region control social behaviours and related mental health conditions? Tumi Moswete Investigating the impact of neuroactive drug exposure on the developmental and functional neurobiology of the vertebrate brain
Trevor Au Yeung Investigating the interactions of incretin hormone mimetics with hypothalamo-neurohypophysial system arginine vasopressin and oxytocin release Yolanda Li Development of dendritic signal processing in the brain: a role for GABAergic interneurons?

Current First Years

Brent Foster Decoding signal computation in pluripotent stem cells Yana Skvortsova The molecular basis of regulating branched microtubule nucleation
Chris Slack Investigating the structure, function and dynamics of the P2X7 receptor ballast domain Ashvini Wijayapala Rhomboid proteolysis: a novel regulator of synaptic function
Krishna Kerai Maintaining human lung – the role of fibroblasts and lipids in alveolar regeneration Louis Grelet How visual systems are adapted to their environments
Maddie Vincent Unlocking the molecular mechanisms governing stem cell dormancy Victoria Lievens Defining the neuronal autophagosome assembly site: spatiotemporal control ATG9A trafficking in human iPSC-derived neurons
Michael Perret Developing an axenic media to grow the currently uncultivable Mycobacterium leprae Ciara Brennan Defining the role of astrocytes in neuronal health and the implications of neuroinflammation
Amy Jones Role of cholesterol and cholesterol metabolites in brain development Raven Huiberts Standing up to threats: Understanding the neural mechanisms underpinning threat-related changes in balance control
Rose Pugh Mechanisms of colour change in chameleon prawns – from genes to sensory ecology Olivia Rose Novel targets for overcoming antimicrobial resistance and tolerance: multikinase network signalling in Burkholderia pseudomallei