University of the West of England (UWE) student profiles

Current Second Years
Current First Years

Current Second Years

Sioned Heal

Standard studentship with associate partner: In collaboration with Bristol + University of the West of England (UWE) 

Sioned graduated from the University of Bristol in 2020 with an Msci in Biochemistry. Her final year project was spent in Jeremy Henley’s lab studying the role of sentrin specific proteases (SENPs) in regulating the SUMOylation status of known SUMO targets, specifically the Rho GDP-dissociation inhibitor (RhoGDI).

Sioned will continue pursuing this area of interest by undergoing a PhD project in Bristol under the supervision of Prof Jeremy Henley focusing on the regulation of neuronal energy production by SUMOylation. Here, the SUMOylation status of mitochondrial proteins will be studied and associated with changes in neuronal metabolism. Part of the project will be undertaken in UWE under the supervision of Dr Tim Craig, where the Seahorse XFe24 will be used to measure key metabolic parameters and determine how changes in protein SUMOylation may affect metabolism.

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Celia Mellor

Standard studentship with associate partner: In collaboration with University of the West of England (UWE) + Bristol 

Celia graduated from the University of Bristol in 2020 with a BSc in Biochemistry. Using molecular dynamics, docking and in vitro techniques her final year project investigated potential inhibitors of P. falciparum’s lactate dehydrogenase in the lab of Dr Richard Sessions. This experience, along with a summer studentship with Dr Mike Jones, attempting to covalently link phycocyanin to purple bacteria reaction centres to develop biophotovoltaics, confirmed her keen interest in molecular biology.

Technology plays a vital role in aiding scientific discovery and Celia’s PhD project will use correlative microscopy and impedance spectroscopy to study changes in cell physiology for the use in bioreactors. The project is supervised by Professors Richard Luxton and Paul Verkade in a joint venture between UWE and the University of Bristol.

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Current First Years

Asheesh Sharma

Standard studentship with associate partner: In collaboration with University of the West of England (UWE) + Bristol 

Asheesh graduated from the University of Bristol and University of West of England in 2016 with an MSc in Robotics. During his research project, he developed a swarm of physically connected agents and studied their use as constituents in free form soft-actuators, where their properties allow different swarm behaviour to emerge, leading to a specific morphology.

His PhD is based at the University of Bristol and the University of West of England. The project investigates the use of 3D camera systems to assess the body conditioning and behaviour of cattle. The project is supervised by Dr Andrew Dowsey (UOB), Dr Tilo Burghardt (UOB), Dr Melvyn Smith (UWE), and Dr Mark Hansen (UWE).

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