PROJECT TITLE |
MAIN / ROTHAMSTED |
HOST INSTITUTION |
KEYWORDS |
A Covalent Phage Display Approach for the Discovery of Lipoteichoic Acid Synthase Inhibitors |
Dr Scott Lovell |
University of Bath |
Covalent Drug Discovery, Peptide Phage Display, Antibiotic Resistance, Structural Biology, Chemical Proteomics |
Ageing and body clock rhythms: The importance of a social network |
Prof Hugh Piggins |
University of Bristol |
socializing, sex differences, sleep, cognition, mouse |
Aging before birth: identifying influences of modifiable maternal lifestyle on telomere length |
Prof Rosalind John |
Cardiff University |
Healthy aging, Maternal diet and nutrition, Telomeres, Human stem cells, Intervention |
Applying integrative microbiomics to understand the health threats of environmental microbiomes |
Dr Anne Leonard |
University of Exeter (Penryn) |
Bioinformatics, Integrative microbiomics, Antimicrobial resistance, Microbiology, Ecology |
Autophagy and the integrated stress response in neurodegeneration: how endomembrane trafficking shapes human neuronal/glial interactions during stress |
Prof Jon Lane |
University of Bristol |
Autophagy, endocytosis, neurons, glia, iPSCs. |
Does sex really matter? Quantifying the importance of sex-disaggregated analysis for improving experimental reproducibility in an experimental fish model *CASE |
Dr Robert Ellis |
University of Exeter (Streatham/St Luke’s) |
Ecotoxicology, Physiology, Animal Husbandry, Sex-disaggregation, Host-pathogen interaction |
Joint function throughout the life course |
Prof Emily Rayfield |
University of Bristol |
Zebrafish, Skeleton, loading, genes, ageing |
Mechanism of free fatty acid protection against SARS-CoV2 viral replication |
Prof Paul Verkade |
University of Bristol |
SARS-CoV2, Free fatty acids, cryo electron tomography, correlative light electron microscopy, membrane remodelling |
Non-genetic paternal effects on offspring reproduction and health: mechanisms and evolutionary consequences in a bird model system |
Dr Barbara Tschirren |
University of Exeter (Penryn) |
Developmental Origins of Health, Epigenetics, Reproductive Health and Behaviour, Fertility and Sustainable Animal Breeding, Mechanisms of Evolutionary Change |
The impact of meal-feeding on human mental and metabolic health |
Prof James Betts |
University of Bath |
Feeding patterns, Mental health, Metabolic health, Hypothalamo-pituitary-adrenal axis, Human volunteers |
The making of a pathogen: the interaction between virulence- and antibiotic resistance evolution |
Dr Michiel Vos |
University of Exeter (Penryn) |
antimicrobial resistance, virulence, genomics, experimental evolution, opportunistic pathogens |
Understanding cellular interactions in a 3D bioprinted model of the glomerulus |
Dr James Armstrong |
University of Bristol |
Kidney, cell biology, bioprinting, biomaterials, tissue engineering |
Understanding receptor-mediated mechanosensing and signalling in cell barrier function during tissue homeostasis and stress responses *AP *JD |
Prof Anne Ridley / Dr Alexander Greenhough |
University of Bristol (apply through here) / University of the West of England |
Cell biology, Mechanosensing, Signalling, Omics, Bioinformatics |
Understanding the cellular processes that support pattern separation in the hippocampal dentate gyrus and how ageing affects our memory |
Dr Denize Atan |
University of Bristol |
Ageing, Pattern separation, Dentate gyrus, Memory, Computational modelling |
Understanding the genetic basis of reproductive strategy in a parasitic nematode system |
Dr Vicky Hunt |
University of Bath |
Reproduction, Parasites, Genetics, small RNA, Nematodes |
Understanding the role of ketone bodies in the regulation of erythropoietin production |
Dr Javier Gonzalez |
University of Bath |
Human Physiology, Cell Signalling, Metabolism, Renal Physiology |
U-RHYTHM: developing a novel technology for the investigation of tissue-level thyroid and sex hormone dynamics in humans |
Prof Stafford Lightman |
University of Bristol |
Biorhythms, Automated sampling, Hormone:plastic interfaces, Sex hormones, Thyroid hormone |