Improving animal and human health and wellbeing across the lifecourse.
*CASE: These are CASE DTP studentships. As part of the programme, you will be required to undertake a placement with the CASE partner for a minimum of 3 months.
*AP: These are Standard DTP studentships with an associate partner where you will be required to spend time with each of the partners. You will be asked to apply to one of the partners (as listed in the ‘Host Institution’ column), but this is just for administration purposes. You will then be registered for your postgraduate studies at one of the partner universities of the lead supervisors. Your registered university will be confirmed by the DTP following the interview stage of the selection process.
| PROJECT TITLE | MAIN / ROTHAMSTED / LEAD SUPERVISOR | HOST INSTITUTION | KEYWORDS |
| Aging before birth: identifying prenatal influences of lifestyle on telomeres and the epigenetic clock | Prof Rosalind John | Cardiff University | Fetal programming, telomeres, epigenetic clock, maternal diet and nutrition, healthy aging |
| Antimicrobial resistance mechanisms in the presence of sub-inhibitory antibiotics and the microbiome | Prof Eshwar Mahenthiralingam | Cardiff University | Antimicrobial resistance, the microbiome, bacteria virulence molecular microbiology and genomics, cystic fibrosis microbiology, proteomics |
| Combatting brain and body ageing through exercise | Prof Hugh Piggins | University of Bristol | Exercise, aging, circadian, metabolism, cardiovascular |
| Dietary strategies to target adipose tissue inflammation in ageing | Prof Dylan Thompson | University of Bath | Nutrition, ageing, inflammation, adipose tissue, sarcopaenia |
| Differentiated normal cell identity and epigenetic barriers to trans-differentiation and reprogramming *CASE | Prof Adele Murrell | University of Bath | Stem cells, epigenetic memory, mathematical modelling, cell identity |
| Exploring joint mechanics and the relationship between shape, strain and cellular behavior through life | Dr Chrissy Hammond | University of Bristol | Joints, zebrafish, biomechanics, development, cells |
| Host specialisms in bacterial pathogens | Prof Edward Feil | University of Bath | Host adaptation, genomics, infectious disease, bioinformatics, bacteria |
| Interplay between cholesterol homeostasis and neural development *AP | Prof Meng Li / Prof Yuqin Wang | Cardiff University (apply here) / Swansea University | Neurodevelopment, neural stem cell, cholesterol metabolism, mass spectrometry, hedgehog signalling |
| Investigating the time course of vitamin D storage in human adipose and skeletal muscle and the relationship to skeletal muscle protein synthesis | Dr Raquel Revuelta Iniesta | University of Exeter (St Luke’s) | Vitamin D, human, skeletal muscle, protein synthesis, adipocytes |
| Phenotypic and genotypic diversity in moraxella catarrhalis: Using population biology to understand antimicrobial resistance and pathogenesis *AP | Dr Darryl Hill / Dr Lynne Lawrance | University of Bristol (apply here) / University of the West of England; UWE | Moraxella, antimicrobial resistance, infection, genomics, bioinformatics |
| Skeletal dysplasia: establishing metabolic and nutritional requirements to manage health risks | Prof James Betts | University of Bath | Physiology, nutrition, metabolism, achondroplasia, obesity |
| Skeletal muscle nitrate metabolism as a modulator of cardiovascular health in ageing | Prof Anni Vanhatalo | University of Exeter (St Luke’s) | Biochemistry and nitric oxide biology, skeletal muscle, dietary interventions, cardiovascular health, ageing |
| Tackling antibiotic resistance through blocking of signalling pathways | Dr Susanne Gebhard | University of Bath | Microbiology, antibiotic resistance, signal transduction, drug development, molecular biology |
| The Father Factor: Non-genetic paternal influences on offspring reproduction and health | Dr Barbara Tschirren | University of Exeter (Penryn) | Developmental origins of health, epigenetics, paternal effects, reproductive health, Fertility |
| The relevance of transposable element dynamics for host-parasite interactions | Dr Vicky Hunt | University of Bath | Parasites, transposable elements, genetics, small RNA, helminths |
| The role of GABA signalling in the electrical timekeeping of the master circadian clock to drive circadian rhythms | Dr Mino Belle | University of Exeter (Streatham) | Biological clock, circadian rhythms, electrophysiology, imaging, GABA |
| To swim or to struggle: how tadpole motor circuits reconfigure themselves in a fraction of a second | Dr Joel Tabak | University of Exeter (Streatham) | Neural networks, mathematical models, locomotion, development, connectome |
| Ultra-high-throughput directed evolution of antimicrobials using droplet microfluidics | Dr Fabrice Gielen | University of Exeter (Streatham) | Antimicrobial, microfluidics, evolution, high-throughput screening, bacteriophage |
| Understanding transcriptional control of autophagy during epithelial homeostasis and microenvironmental stress *AP | Dr Jon Lane / Dr Alexander Greenhough | University of Bristol (apply here) / University of the West of England; UWE | Cell biology, bioinformatics, autophagy, hypoxia, stem cells |
| Unlocking the psychopharmacology of psychedelics *CASE | Prof Emma Robinson | University of Bristol | Research Domains Criteria, positive valence system, animal behaviour, electrophysiology, cognitive neuroscience, prefrontal cortex |
| Using microbial networks to quantify transmission dynamics of bovine tuberculosis *CASE | Dr Xavier Harrison | University of Exeter (Penryn) | Gut microbiome, disease transmission, zoonoses, epidemiology, pathogens |