Bioscience for an integrated understanding of health

Improving animal and human health and wellbeing across the lifecourse.

*CASE: These are CASE DTP studentships. As part of the programme, you will be required to undertake a placement with the CASE partner for a minimum of 3 months.

*AP: These are Standard DTP studentships with an associate partner where you will be required to spend time with each of the partners. You will be asked to apply to one of the partners (as listed in the ‘Host Institution’ column), but this is just for administration purposes.  You will then be registered for your postgraduate studies at one of the partner universities of the lead supervisors.  Your registered university will be confirmed by the DTP following the interview stage of the selection process.

*JD: This project in collaboration with the University of Bristol and the University of the West of England (UWE) is subject to a joint degree award. Successful applicants will be registered at both these institutions, and graduates will be awarded a joint degree from these two institutions upon successful completion of the PhD programme.


A Covalent Phage Display Approach for the Discovery of Lipoteichoic Acid Synthase Inhibitors Dr Scott Lovell University of Bath Covalent Drug Discovery, Peptide Phage Display, Antibiotic Resistance, Structural Biology, Chemical Proteomics
Ageing and body clock rhythms: The importance of a social network Prof Hugh Piggins University of Bristol socializing, sex differences, sleep, cognition, mouse
Aging before birth: identifying influences of modifiable maternal lifestyle on telomere length Prof Rosalind John Cardiff University Healthy aging, Maternal diet and nutrition, Telomeres, Human stem cells, Intervention
Applying integrative microbiomics to understand the health threats of environmental microbiomes Dr Anne Leonard University of Exeter (Penryn) Bioinformatics, Integrative microbiomics, Antimicrobial resistance, Microbiology, Ecology
Autophagy and the integrated stress response in neurodegeneration: how endomembrane trafficking shapes human neuronal/glial interactions during stress Prof Jon Lane University of Bristol Autophagy, endocytosis, neurons, glia, iPSCs.
Does sex really matter? Quantifying the importance of sex-disaggregated analysis for improving experimental reproducibility in an experimental fish model *CASE Dr Robert Ellis University of Exeter (Streatham/St Luke’s) Ecotoxicology, Physiology, Animal Husbandry, Sex-disaggregation, Host-pathogen interaction
Joint function throughout the life course Prof Emily Rayfield University of Bristol Zebrafish, Skeleton, loading, genes, ageing
Mechanism of free fatty acid protection against SARS-CoV2 viral replication Prof Paul Verkade University of Bristol SARS-CoV2, Free fatty acids, cryo electron tomography, correlative light electron microscopy, membrane remodelling
Non-genetic paternal effects on offspring reproduction and health: mechanisms and evolutionary consequences in a bird model system Dr Barbara Tschirren University of Exeter (Penryn) Developmental Origins of Health, Epigenetics, Reproductive Health and Behaviour, Fertility and Sustainable Animal Breeding, Mechanisms of Evolutionary Change
The impact of meal-feeding on human mental and metabolic health Prof James Betts University of Bath Feeding patterns, Mental health, Metabolic health, Hypothalamo-pituitary-adrenal axis, Human volunteers
The making of a pathogen: the interaction between virulence- and antibiotic resistance evolution Dr Michiel Vos University of Exeter (Penryn) antimicrobial resistance, virulence, genomics, experimental evolution, opportunistic pathogens
Understanding cellular interactions in a 3D bioprinted model of the glomerulus Dr James Armstrong University of Bristol Kidney, cell biology, bioprinting, biomaterials, tissue engineering
Understanding receptor-mediated mechanosensing and signalling in cell barrier function during tissue homeostasis and stress responses *AP *JD Prof Anne Ridley / Dr Alexander Greenhough University of Bristol (apply through here) / University of the West of England Cell biology, Mechanosensing, Signalling, Omics, Bioinformatics
Understanding the cellular processes that support pattern separation in the hippocampal dentate gyrus and how ageing affects our memory Dr Denize Atan University of Bristol Ageing, Pattern separation, Dentate gyrus, Memory, Computational modelling
Understanding the genetic basis of reproductive strategy in a parasitic nematode system Dr Vicky Hunt University of Bath Reproduction, Parasites, Genetics, small RNA, Nematodes
Understanding the role of ketone bodies in the regulation of erythropoietin production Dr Javier Gonzalez University of Bath Human Physiology, Cell Signalling, Metabolism, Renal Physiology
U-RHYTHM: developing a novel technology for the investigation of tissue-level thyroid and sex hormone dynamics in humans Prof Stafford Lightman University of Bristol Biorhythms, Automated sampling, Hormone:plastic interfaces, Sex hormones, Thyroid hormone