Bioscience for an integrated understanding of health

Improving animal and human health and wellbeing across the lifecourse.

*CASE: These are CASE DTP studentships. As part of the programme, you will be required to undertake a placement with the CASE partner for a minimum of 3 months.
*AP: These are Standard DTP studentships with an associate partner where you will be required to spend approximately a total of 50% of your time with each of the partners. You will be registered at one of the partner universities of the lead supervisors.

Project title Main / Rothamsted supervisor Host institution Keywords
Aging before birth: identifying early-life influences on telomeres and the epigenetic clock Prof Rosalind John Cardiff University Aging, Telomeres, Epigenetics, Maternal lifestyle, Fetal programming
Combatting brain and body ageing through exercise Prof Hugh Piggins University of Bristol Exercise, aging, circadian, metabolism, cardiovascular
Developing better biopharmaceuticals using biomolecular simulation and design *CASE Dr Marc van der Kamp University of Bristol T cell receptor, biomolecular simulation, biopharmaceuticals, protein-protein interaction, protein design
Divergent trajectories of cortical development regulated by differential NMDA receptor populations Dr Michael Ashby University of Bristol Neuroscience, brain development, synapse, plasticity, neural circuit
Elucidating the role of mechano-sensitive miRNAs in cartilage homeostasis: a multi-organism study Dr Emma Blain Cardiff University Mechanobiology, cartilage, zebrafish, microRNAs
Linking age-related joint degradation to diet by bone metabolism and SUMOylation *AP Dr Chrissy HammondDr Tim Craig University of Bristol (apply here) / University of the West of England (UWE) Bone health, Diabetes, SUMOylation, metabolism, ageing
Mixing it up: building the tools required for next-generation molecular microbiologists to study polymicrobial disease Prof Eshwar Mahenthiralingam Cardiff University Antimicrobial resistance, polymicrobial disease, genomics, cystic fibrosis microbiology, proteomics
Modelling the effect of ageing on Drosophila and mouse clock neurons Prof James Hodge University of Bristol Drosophila, electrophysiology, computational modelling, circadian rhythms, ageing
Tackling antibiotic resistance through blocking of signalling pathways Dr Susanne Gebhard University of Bath Microbiology, antibiotic resistance, signal transduction, drug development, molecular biology
Ultra-high-throughput directed evolution of antimicrobials using droplet microfluidics Dr Fabrice Gielen University of Exeter (Streatham) Antimicrobial, microfluidics, evolution, high-throughput screening, bacteriophage
Unravelling the cause of Parkinson’s Disease in molecular detail *CASE Prof Matthew Crump University of Bristol NMR Spectroscopy, Protein Biochemistry, Chemical Biology