Bioscience for an integrated understanding of health

Improving animal and human health and wellbeing across the lifecourse.

*CASE: These are CASE DTP studentships. As part of the programme, you will be required to undertake a placement with the CASE partner for a minimum of 3 months.

*AP: These are Standard DTP studentships with an associate partner where you will be required to spend time with each of the partners. You will be asked to apply to one of the partners (as listed in the ‘Host Institution’ column), but this is just for administration purposes.  You will then be registered for your postgraduate studies at one of the partner universities of the lead supervisors.

 

PROJECT TITLE MAIN / ROTHAMSTED / LEAD SUPERVISOR HOST INSTITUTION KEYWORDS
Aging before birth: identifying prenatal influences of lifestyle on telomeres and the epigenetic clock Prof Rosalind John Cardiff University Fetal programming, telomeres, epigenetic clock, maternal diet and nutrition, healthy aging
Antimicrobial resistance mechanisms in the presence of sub-inhibitory antibiotics and the microbiome Prof Eshwar Mahenthiralingam Cardiff University Antimicrobial resistance, the microbiome, bacteria virulence molecular microbiology and genomics, cystic fibrosis microbiology, proteomics
Combatting brain and body ageing through exercise Prof Hugh Piggins University of Bristol Exercise, aging, circadian, metabolism, cardiovascular
Dietary strategies to target adipose tissue inflammation in ageing Prof Dylan Thompson University of Bath Nutrition, ageing, inflammation, adipose tissue, sarcopaenia
Differentiated normal cell identity and epigenetic barriers to trans-differentiation and reprogramming *CASE Prof Adele Murrell University of Bath Stem cells, epigenetic memory, mathematical modelling, cell identity
Exploring joint mechanics and the relationship between shape, strain and cellular behavior through life Dr Chrissy Hammond University of Bristol Joints, zebrafish, biomechanics, development, cells
Host specialisms in bacterial pathogens Prof Edward Feil University of Bath Host adaptation, genomics, infectious disease, bioinformatics, bacteria
Interplay between cholesterol homeostasis and neural development *AP Prof Meng Li / Prof Yuqin Wang Cardiff University (apply here) / Swansea University Neurodevelopment, neural stem cell, cholesterol metabolism, mass spectrometry, hedgehog signalling
Investigating the time course of vitamin D storage in human adipose and skeletal muscle and the relationship to skeletal muscle protein synthesis Dr Raquel Revuelta Iniesta University of Exeter (St Luke’s) Vitamin D, human, skeletal muscle, protein synthesis, adipocytes
Phenotypic and genotypic diversity in moraxella catarrhalis: Using population biology to understand antimicrobial resistance and pathogenesis *AP Dr Darryl Hill / Dr Lynne Lawrance University of Bristol (apply here) / University of the West of England; UWE Moraxella, antimicrobial resistance, infection, genomics, bioinformatics
Skeletal dysplasia: establishing metabolic and nutritional requirements to manage health risks Prof James Betts University of Bath Physiology, nutrition, metabolism, achondroplasia, obesity
Skeletal muscle nitrate metabolism as a modulator of cardiovascular health in ageing Prof Anni Vanhatalo University of Exeter (St Luke’s) Biochemistry and nitric oxide biology, skeletal muscle, dietary interventions, cardiovascular health, ageing
Tackling antibiotic resistance through blocking of signalling pathways Dr Susanne Gebhard University of Bath Microbiology, antibiotic resistance, signal transduction, drug development, molecular biology
The Father Factor: Non-genetic paternal influences on offspring reproduction and health Dr Barbara Tschirren University of Exeter (Penryn) Developmental origins of health, epigenetics, paternal effects, reproductive health, Fertility
The relevance of transposable element dynamics for host-parasite interactions Dr Vicky Hunt University of Bath Parasites, transposable elements, genetics, small RNA, helminths
The role of GABA signalling in the electrical timekeeping of the master circadian clock to drive circadian rhythms Dr Mino Belle University of Exeter (Streatham) Biological clock, circadian rhythms, electrophysiology, imaging, GABA
To swim or to struggle: how tadpole motor circuits reconfigure themselves in a fraction of a second Dr Joel Tabak University of Exeter (Streatham) Neural networks, mathematical models, locomotion, development, connectome
Ultra-high-throughput directed evolution of antimicrobials using droplet microfluidics Dr Fabrice Gielen University of Exeter (Streatham) Antimicrobial, microfluidics, evolution, high-throughput screening, bacteriophage
Understanding transcriptional control of autophagy during epithelial homeostasis and microenvironmental stress *AP Dr Jon Lane / Dr Alexander Greenhough University of Bristol (apply here) / University of the West of England; UWE Cell biology, bioinformatics, autophagy, hypoxia, stem cells
Unlocking the psychopharmacology of psychedelics *CASE Prof Emma Robinson University of Bristol Research Domains Criteria, positive valence system, animal behaviour, electrophysiology, cognitive neuroscience, prefrontal cortex
Using microbial networks to quantify transmission dynamics of bovine tuberculosis *CASE Dr Xavier Harrison University of Exeter (Penryn) Gut microbiome, disease transmission, zoonoses, epidemiology, pathogens